What is a cathinone derivative?
Cathinone derivatives are the β-keto (βk) analogues of a corresponding phenethylamine. The group includes several substances that have been used as active pharmaceutical ingredients (API) of medicinal products, e.g. amfepramone (diethylpropion; Figure 2).
What is the best Cathinone?
Some of the best recognized synthetic cathinones (i.e., those most popular in the current scientific literature and on the clandestine market) include methcathinone (MCAT; 2), mephedrone (3), methylenedioxypyrovalerone (MDPV; 4), and α-pyrrolidinovalerophenone (α-PVP; 5; “flakka”) (Figure 1).
What schedule drug is Cathinone?
Schedule I stimulant
Cathine is a Schedule IV stimulant, and cathinone is a Schedule I stimulant under the Controlled Substances Act, meaning that it has a high potential for abuse, no currently accepted medical use in treatment in the United States, and a lack of accepted safety for use under medical supervision.
How are synthetic cathinones detected?
Synthetic cathinones can be detected in blood, urine and stomach content in both pre- and postmortem specimens. They can be characterized qualitatively and quantitatively using gas chromatography–mass spectrometry (GC–MS) or liquid chromatography–mass spectrometry (LC–MS) techniques.
Is khat plant legal?
It is a specifically controlled substance in some countries including Canada, Germany, the United Kingdom, and the United States. By contrast, the production, sale, and consumption are legal in the nations where its use is traditional of those cultures, including Djibouti, Kenya, Uganda, Ethiopia, and Yemen.
Is khat legal in USA?
Is Khat Legal in the US. The khat leaf is not illegal in the United States, but the drug in the khat leaf, Cathinone, is a Schedule I controlled substance, making it among the most tightly regulated in the United States.
What is the ACMD?
The Advisory Council on the Misuse of Drugs ( ACMD) is a British statutory advisory non-departmental public body, which was established under the Misuse of Drugs Act 1971 .
How does the ACMD measure the harms of a drug?
submissions from special interest groups and the general public. In order to have a rough but quantitative measure of the harms of a drug, the ACMD uses a risk assessment matrix, where nine different aspects of harm for each drug are evaluated:
What is the ACMD’s risk assessment matrix?
In order to have a rough but quantitative measure of the harms of a drug, the ACMD uses a risk assessment matrix, where nine different aspects of harm for each drug are evaluated:
Should scientific advice on drug policy be removed from the ACMD?
“ACMD changes: removing scientific advice from drug policy is a catastrophically bad idea”. London: Blogs.telegraph.co.uk. Archived from the original on 2010-12-10. Retrieved 2011-01-23. ^ Johnson, Wesley (2010-12-06).