What disease causes ichthyosis vulgaris?
Diseases that can trigger it include long-term kidney failure, different types of cancer (especially lymphoma), sarcoidosis, and infections such as leprosy and HIV. Acquired ichthyosis vulgaris can show up before the person has signs of the triggering disease.
What causes acquired ichthyosis?
In adults, the disease is called acquired ichthyosis vulgaris, and can be caused by other diseases, including kidney failure, certain cancers, sarcoidosis, leprosy, and human immunodeficiency virus (HIV).
Who does ichthyosis vulgaris affect?
Ichthyosis vulgaris is a fairly common disorder that affects approximately one in 250 persons in the United States. Males and females are affected in equal numbers.
What is Pityriasis Rotunda?
Pityriasis rotunda (PR) is a rare, idiopathic, and chronic dermatosis characterized by discrete, round, scaly, pigmented patches. [1, 2, 3, 4, 5, 6, 7, 8, 9] Pityriasis rotunda may be associated with systemic diseases (eg, hepatocellular carcinoma) in certain racially predisposed groups.
Is ichthyosis vulgaris an autoimmune disease?
The association of autoimmune conditions with acquired ichthyosis could indicate that an abnormal host immune response, probably against components of the granular cell layer in particular the keratohyalin granules, may have a role in the pathogenesis.
Does acquired ichthyosis go away?
There are at least 20 different types of ichthyosis. Some types are inherited at birth and other types are acquired during adulthood. There’s no cure for ichthyosis, but a daily skincare routine usually keeps the symptoms mild and manageable.
What gene mutation causes ichthyosis?
Ichthyosis vulgaris is caused by loss-of-function mutations in the filaggrin gene (FLG) and is characterized clinically by xerosis, scaling, keratosis pilaris, palmar and plantar hyperlinearity, and a strong association with atopic disorders.
What causes ichthyosis vulgaris?
The older skin cells build up on the skin’s surface, causing the scale and thickened skin. Acquired ichthyosis vulgaris has a different cause. A disease usually triggers it. Diseases that can trigger it include long-term kidney failure, different types of cancer (especially lymphoma), sarcoidosis, and infections such as leprosy and HIV.
What is acquired ichthyosis vulgaris (fish scale disease)?
Acquired ichthyosis vulgaris, also known as fish scale disease because of the pattern in which dry, dead skin accumulates, is the most common type of acquired ichthyosis. This type of ichthyosis appears most often in adulthood and may appear any time before or after the diagnosis of a systemic condition.
What is acquired ichthyosis (AI)?
Acquired ichthyosis. Acquired ichthyosis (AI) is a nonhereditary cutaneous disorder characterized by dry, rough skin with prominent scaling that involves significant portions of the body.
Can ichthyosis vulgaris go undiagnosed?
The scales of ichthyosis vulgaris, sometimes called fish scale disease or fish skin disease, can be present at birth, but usually first appear during early childhood. Sometimes, mild cases of ichthyosis vulgaris go undiagnosed because they’re mistaken for extremely dry skin.