What is the difference between multifocal and multicentric breast cancer?
The presence of two or more foci of cancer within the same breast quadrant is defined as multifocal, while the presence of two or more foci of cancer in different quadrants of the same breast is defined as multicentric.
How common is multicentric breast cancer?
Introduction. Multifocal and multicentric breast cancer (MMBC) is common, with a reported incidence of 9–75%. Incidence varies according to the extent of breast tissue sampling, but this wide range of reported incidence also reflects the lack of a standard definition of MMBC.
What is treatment for multicentric breast cancer?
There are several treatment options available for multifocal breast cancer. These include lumpectomy, mastectomy, radiation therapy, hormonal therapy, and chemotherapy.
Which type of breast cancer is multicentric and bilateral?
Multiple breast cancers may present with different clinical and biological characteristics. The data indicate that multifocal (MF), multicentric (MC), and bilateral synchronous (BS) breast cancers (BC) are more aggressive and have an equivalent or moderately poorer survival rate compared with unilateral cases.
What does multicentric breast cancer mean?
Breast cancer in which there is more than one tumor, all of which have formed separately from one another. The tumors are likely to be in different quadrants (sections) of the breast. Multicentric breast cancers are rare.
What does multicentric mean?
adjective. originating in or involving several parts of the body or of an organ. treatment of multicentric lymphoma in dogs. (of a chromosome) having more than one centromere.
What is the survival rate of multicentric breast cancer?
The disease-free survival rates in the multifocal/multicentric group at 5 and 10 years were 75% and 71%, respectively, versus 87% and 78% at 10 years (p = 0.01). On multivariate analysis, multifocal/multicentric disease was no longer associated with worse disease-free survival.
What is a multicentric breast tumor?
A multicentric breast cancer is a term given to a breast cancer where there are two or more breast cancers separated by normal breast tissue (often taken as 5 cm of separation 4). It is related to but distinct from the term multifocal breast cancer.
Which breast cancer is multicentric?
A multicentric breast cancer is a term given to a breast cancer where there are two or more breast cancers separated by normal breast tissue (often taken as 5 cm of separation 4). It is related to but distinct from the term multifocal breast cancer. histopathologically, discontinued tumors with intra-ductal invasion.
Can breast cancer be two lumps?
Multifocal breast cancer occurs when there are two or more tumors in the same breast. All of the tumors begin in one original tumor. The tumors are also all in the same quadrant — or section — of the breast. Multicentric breast cancer is a similar type of cancer.
What is multicentric hepatoma?
Multicentric occurrence (MO) and intrahepatic metastasis (IM) are characteristic in the development of HCC with chronic liver diseases that are caused by hepatitis B virus (HBV) or hepatitis C virus (HCV)[8-13].
What is multicentric carcinoma?
Breast cancer in which there is more than one tumor, all of which have formed separately from one another. The tumors are likely to be in different quadrants (sections) of the breast.
What does a multicentric breast cancer mean?
A multicentric breast cancer is a term given to a breast cancer where there are two or more breast cancers separated by normal breast tissue (often taken as 5 cm of separation 4). It is related to but distinct from the term multifocal breast cancer. At a pathological level It can also mean 2
What is the incidence of multifocal and multicentric breast cancer?
The incidence of multifocal (MF) and multicentric (MC) breast cancer has a wide variation among different clinical studies, mostly due to the lack of a standardized classification and definition of these two separate entities. The optimal surgical treatment for multiple ipsilateral breast cancer remains a long debated subject.
What is multicentric Castleman disease?
Summary Summary. Multicentric Castleman disease (MCD) is a rare disease that affects the lymph nodes and related tissues. It is a form of Castleman disease that is “systemic” and involves multiple regions of lymph nodes (as opposed to unicentric Castleman disease, which involves a single lymph node or single region of lymph nodes).
Do multicentric tumors affect DFS in breast cancer patients?
M/M imparts an unfavorable prognosis on the DFS of breast cancer patients in comparison to unifocal tumors and the presence of multifocal/multicentric tumors were associated with advanced pT and pN stages.