Can you take fluoxetine and duloxetine together?
Using FLUoxetine together with DULoxetine can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision.
Is duloxetine better than fluoxetine?
Is Cymbalta or Prozac more effective? One study reviewed many studies comparing Cymbalta, Prozac, and another medication called Effexor, to placebo. Cymbalta and Prozac were found to be similar in efficacy and safety for patients with depression.
How much weight do you lose on duloxetine?
According to an analysis of 10 clinical studies, acute treatment with duloxetine in major depressive disorder patients would cause a mean body weight loss of 0.5 kg (0.2 kg with placebo).
How common is weight gain with duloxetine?
In the 34-week studies, a weight gain greater than 7% of the baseline weight (at the start of the study) occurred in 8.6% of patients taking Cymbalta 40 mg twice a day (186 patients), and in 12.8% of those taking Cymbalta 60 mg twice day (195 patients), compared to 5.7% weight gain with placebo (192 patients).
How do I switch from duloxetine to Prozac?
Switch medication from fluoxetine to duloxetine. Before day 1: reduce dosage of fluoxetine with about 20 mg per week. Day 1: when a dosage of 20 mg/day is reached, stop fluoxetine.
Does Prozac cause weight gain?
Prozac is not alone in causing this potential dreaded side effect; many antidepressants can potentially lead to weight gain, particularly with long-term use. 1In fact, Prozac is actually considered one of the weight-neutral antidepressants, meaning it doesn’t typically cause weight gain.
Why does duloxetine cause weight loss?
From the above research, it appears that Cymbalta is more likely to cause weight loss in the short-term, possibly due to changes in appetite. During longer-term treatment, some people may experience modest increases in weight.
Does Duloxetine increase appetite?
A lower percentage of duloxetine-treated patients (1.1%) compared with placebo-treated patients (1.4%) reported appetite increased; however, this difference was not significant.