How do you give an NTG infusion?
Initially, 0.25 to 0.5 mcg/kg/minute continuous IV infusion. Titrate by 1 mcg/kg/minute IV every 15 to 20 minutes as tolerated. The usual dosage range is 1 to 5 mcg/kg/minute.
What are side effects of NTG infusion?
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- Bluish-colored lips, fingernails, or palms.
- difficulty with breathing.
- dizziness or lightheadedness.
- headache.
- rapid heart rate.
- sore throat.
- unusual tiredness or weakness.
What is nitroglycerin used for?
Nitroglycerin sublingual tablets are used to treat episodes of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). It is also used just before activities that may cause episodes of angina in order to prevent the angina from occurring.
What is the action of nitroglycerine?
Nitroglycerin causes the relaxation of vascular smooth muscles, causing arteriolar and venous dilatation. It reduces cardiac preload and afterload and reduces coronary artery spasm, decreasing systemic vascular resistance as well as systolic and diastolic blood pressure.
How do you administer a GTN infusion?
Glyceryl trinitrate Administer a 50mg/50mL IV infusion using a Graseby pump. Start at 0.6ml/hour (10micrograms per minute). Titrate upwards in increments of 0.6mL/hour according to blood pressure, headache and chest pain. Max: 6ml/hour.
What meds can you not take with lithium?
Taking lithium along with NSAIDs might increase the risk of lithium side effects. Avoid taking lithium supplements and NSAIDs at the same time. Some NSAIDs include ibuprofen (Advil, Motrin, Nuprin, others), indomethacin (Indocin), naproxen (Aleve, Anaprox, Naprelan, Naprosyn), piroxicam (Feldene), aspirin, and others.
What route is nitroglycerin?
Adults—1 tablet placed under the tongue or between the cheek and gum at the first sign of an angina attack. 1 tablet may be used every 5 minutes as needed, for up to 15 minutes. Do not take more than 3 tablets in 15 minutes.
Is nitroglycerin a beta blocker?
Drugs: Nitrates: nitroglycerin, isosorbide dinitrate. Beta Blockers: propranolol, metoprolol, atenolol. Calcium Channel Blockers: nifedipine, verapamil, diltiazem.
How do you wean a GTN infusion?
Discontinue as per doctors instructions Increase to a maximum of 12 mls per hour in increments of 0.3 – 0.6 mls per hour at approx 30 minute intervals. Increase GTN only in steps of 0.3 ml – 0.6 ml per hour at approx 30 minute intervals. Check BP every 15 minutes on drug increase. Maintain 90 mmHg systolic BP.