How many ATP will we get from palmitoyl CoA?
Considering an average production of 2.5 ATP/NADH and 1.5 ATP/FADH2 using the respiratory chain, you have 108 ATP molecules. However, 2 ATP molecules were consumed during the initial activation of Palmitate to Palmitoyl-CoA which is going to be oxidized in the mitochondria. So, net energy output = (108 – 2) = 106 ATP.
How much ATP can oxidation of palmitate yield?
129 ATP molecules
ATP synthesis Complete oxidation of one palmitate molecule (fatty acid containing 16 carbons) generates 129 ATP molecules.
How much ATP does a 15 carbon fatty acid produce?
The most straightforward way to accomplish this task would be to exit as malate, and then be oxidized and decarboxylated by the malic enzyme. The ME generates NADPH, which is energetically equivalent to NADH. Therefore, total yield of ATP from the C15 fatty acid is: -2+34+15+51-1+21 = 118 ATP.
How many ATP are produced from palmitic acid?
Total ATP produced are = 21 + 14 + 96 = 131 ATP But since 2 ATP is used to activate the fatty acid in the first step Therefore, 131 – 2 = 129 ATP Thus, from the oxidation of one molecule of palmitic acid, the number of ATP molecules released is 129 ATP.
Is palmitate the same as palmitoyl-CoA?
Palmitoyl-CoA is a coenzyme A derivative of palmitate formed by acyl-CoA synthase. In contrast to medium- and short-chain acyl-CoA, palmitoyl-CoA cannot freely diffuse into the mitochondrial matrix.
How many ATPs are produced from the complete oxidation of 2 acetyl-CoA?
12 ATP
So, the correct answer is 12 ATP.
How do you calculate ATP yield?
To obtain the energy yield it is necessary to calculate that net ATP yield which is given by the difference between the total ATP produced and the ATP consumed: 1 FADH2 produces 2 ATP and 1 NADH produces 3 ATP in the election transport chain.
How much ATP does a 12 carbon fatty acid produce?
In addition, two equivalents of ATP are lost during the activation of the fatty acid. Therefore, the total ATP yield can be stated as: (0.5 * n – 1.5) * 14 + 4 – 2 = total ATP….Energy yield.
| Source | ATP | Total |
|---|---|---|
| 1 acetyl CoA | x 10 ATP | = 10 ATP (Theoretically 12 ATP) |
| TOTAL | = 14 ATP |
How many ATP does a 22 carbon fatty acid produce?
How many ATP does a 22 carbon fatty acid produce? This gives us a grand total of 31 NADH, 15 FADH2 and 8 GTP molecules. The 31 NADH produce 77.5 ATP while the 15 FADH2 produce 22,5 ATP along the electron transport chain. The 8 GTP are transformed into 8 ATP.
How palmitoyl-CoA is formed?
Palmitoyl CoA formed from palmitic acid, in the reaction below. This reaction is often referred to as the “activation” of a fatty acid. The activation is catalyzed by palmitoyl-coenzyme A synthetase and the reaction proceeds through a two step mechanism, in which palmitoyl-AMP is an intermediate.
How many ATP is produced from acetyl-CoA?
12 ATP molecules
Acetyl CoA produces 12 ATP molecules accounting for 3 NADH (9 ATP), 1 FADH2 (2 ATP) and 1 GTP (1 ATP) in the TCA cycle and oxidative phosphorylation in the electron transport system.
What is the ATP yield of acetyl CoA?
Then, the 2 molecules of acetyl-CoA enter the TCA cycle and yield 3 NADH, 1 FADH 2 and 1 ATP each. This gives 4 ATP + 2 ATP, 4 + 6 NADH, and 2 FADH 2, a total of 6 ATP, 10 NADH, and 2 FADH. 10 NADH = 25 ATP and 2 FADH 2 = 3 ATP. 4 ATP + 25 ATP + 3 ATP gives 32 ATP, which is the ATP yield of one molecule of glucose.
How many ATP are produced from one palmitic acid molecule?
Complete oxidation of one molecule of palmitic acid yields 129 ATP molecules: Each molecule of acetyl-CoA yields 12 ATP (12 × 8 = 96); FADH 2 yields 2 ATP (7 × 2 = 14); NADH yields 3ATP (7 × 3 = 21); and two high-energy bonds are consumed (-2; ATP → AMP + PP i ). Thus, net ATP production is 129.
How many acetyl-CoA molecules are produced from palmitoyl CoA?
Palmitoyl-CoA yields 8 acetyl-CoA molecules and 14 pairs of hydrogen atoms, by seven cycles through the β -oxidation system.
What is the function of palmitoyl CoA?
Palmitoyl-CoA is a fatty acid coenzyme derivative which plays a key role in fatty acid oxidation and biosynthesis. Hexadecanoyl-coa is part of the Peroxisome pathway. It is a substrate for: Fatty acyl-CoA reductase 1, and Fatty acyl-CoA reductase 2.
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