What is associated with enterovirus 71?

What is associated with enterovirus 71?

Enterovirus 71 Encephalomyelitis Enterovirus 71 (EV71) has been associated with hand, foot, and mouth disease; herpangina; aseptic meningitis; and poliomyelitis-like flaccid paralysis. More recently EV71 has been associated with unusual cases of fulminant encephalitis, pulmonary edema and hemorrhage, and heart failure.

What is Pan enterovirus?

Light Diagnostics Pan-Enterovirus Blend is intended as an indirect immunofluorescence screening reagent for the preliminary identification of enteroviruses from cell culture and not intended for testing directly on human specimens. For in vitro diagnostic use.

Does acyclovir work for enterovirus?

Enteroviruses, however, lack thymidine kinase, and in vitro studies have failed to show any inhibitory effect of acyclovir on them. Thus, acyclovir is believed to work in HFMD by modulating the patient’s own interferon for its antiviral effect.

Does enterovirus have envelope?

According to the Centers for Disease Control and Prevention, enteroviruses cause at least 10–15 million symptomatic infections in the United States each year [1]. These viruses belong to the Picornaviridae family and are small, non-enveloped viruses that have a single stranded positive sense RNA genome.

What is the most serious disease caused by EV71?

Children <4 years of age are particularly susceptible to the most severe forms of EV71-associated neurological disease, including meningitis, brain-stem and/or cerebellar encephalitis, and poliomyelitis-like paralysis. The neurological complications of EV71 infection may occasionally cause permanent paralysis or death.

Is there a vaccine for enterovirus 71?

Enterovirus 71 vaccines To date three vaccines against EV71 have been licensed in China, all using C4 genogroup strains. The efficacy of these three vaccines after two doses immunization ranges from 90.0% to 97.4% after one year of surveillance to 95.1% after two-year follow-up.

What is coxsackievirus A16 and Enterovirus 71?

Enterovirus 71 (EV71) and Coxsackievirus A16 (CVA16) are two viruses commonly responsible for hand, foot and mouth disease (HFMD) in children. The lack of prophylactic or therapeutic measures against HFMD is a major public health concern.

Is acyclovir the same as Valtrex?

Zovirax (acyclovir) and Valtrex (valacyclovir) are antiviral medications that interfere with the replication of herpes viruses and are used to treat shingles, chickenpox, cold sores, and genital herpes.

Is polio an enterovirus?

Poliovirus, the prototypical enterovirus, can cause a subclinical or mild illness, aseptic meningitis, or paralytic poliomyelitis, a disease that has been eradicated in the United States and other developed countries.

How do enteroviruses work?

Enteroviruses can be spread when an infected person sneezes or coughs droplets into the air or on surfaces. A child may then breathe in droplets, or touch a contaminated surface and touch his or her eyes, mouth, or nose. The viruses are treated with supportive care such as pain medicine.

What is another common childhood disease that is caused by an enterovirus often enterovirus 71 )?

First identified in the United States in 1969, enterovirus A71 (EV-A71) is one of more than 100 non-polio enteroviruses. Worldwide, EV-A71 is a common cause of hand, foot, and mouth disease in infants and young children.