What is the interstitial space in the testes?
The interstitial compartment of the testis, which constitutes the area of the organ outside of the testis cords/seminiferous tubules, is comprised of several cell types.
Are Leydig cells large?
They produce testosterone in the presence of luteinizing hormone (LH). Leydig cells are polyhedral in shape, and have a large prominent nucleus, an eosinophilic cytoplasm and numerous lipid-filled vesicles.
Are interstitial cells found in testes?
In males the interstitial cells of Leydig, located in the connective tissue surrounding the sperm-producing tubules of the testes, are responsible for the production and secretion of testosterone.
What do Leydig cells look like?
Leydig cells can be found around seminiferous tubules forming groups of up to ten cells. They are generally described as polygonal cells with eosinophilic cytoplasm and a large round nucleus with a prominent nucleolus. Lipid content is abundant.
What is the role of interstitial cell?
The interstitial cells or Leydig cells are found in male testes. They are attached to seminiferous tubules. These cells are responsible for the secretion of testosterone hormone in the presence of Luteinizing Hormone (LH), which is secreted by the anterior lobe of the pituitary gland.
Where are the interstitial cells of Leydig?
the testes
Leydig cells are interstitial cells located adjacent to the seminiferous tubules in the testes. The best-established function of Leydig cells is to produce the androgen, testosterone, under the pulsatile control of pituitary luteinizing hormone (LH) (9).
What is the interstitial cell?
any of the cells that fill the spaces between other tissues and structures. The interstitial cells of the testis surround the seminiferous tubules and secrete testosterone when stimulated by luteinizing hormone.
What is the purpose of interstitial cells?
Interstitial cells take part in complex signaling interactions with both interstitial and tubular cell populations, which are required for several biological processes, such as steroidogenesis, Sertoli cell function, spermatogenesis, and immune regulation.
What is secreted by the interstitial cells?
testosterone
Leydig cells, L, synthesize and secrete the male sex hormones (e.g., testosterone), and are the principal cell type found in the interstitial supporting tissue, located between the seminiferous tubules.
What is another name for interstitial cell stimulating hormone?
Luteinizing hormone
Luteinizing hormone (LH; also called interstitial-cell-stimulating hormone, or ICSH) is another gonadotropin, a glycoprotein with a molecular weight of 26,000 in humans.
What is the interstitial gland?
Medical Definition of interstitial gland : any of the groups of Leydig cells of the testis.