What is the use of piperazine?
Anthelmintics are used in the treatment of worm infections. Piperazine is used to treat: common roundworms (ascariasis) and. pinworms (enterobiasis; oxyuriasis).
What class of drug is piperazine?
Piperazine belongs to the family of medicines called anthelmintics. Anthelmintics are used in the treatment of worm infections.
What is piperazine made of?
Piperazine is an azacycloalkane that consists of a six-membered ring containing two nitrogen atoms at opposite positions. It has a role as an anthelminthic drug. It is a saturated organic heteromonocyclic parent, an azacycloalkane and a member of piperazines. It is a conjugate base of a piperazinium(2+).
How do you make piperazine?
Although many piperazine derivatives occur naturally, piperazine itself can be synthesized by reacting alcoholic ammonia with 1,2-dichloroethane, by the action of sodium and ethylene glycol on ethylene diamine hydrochloride, or by reduction of pyrazine with sodium in ethanol.
Can humans take piperazine?
piperazine, also called hexahydropyrazine, anthelmintic drug used in the treatment of intestinal roundworm infection in humans and domestic animals (including poultry) and against pinworm infection in humans. It is administered orally, in repeated doses, usually as the citrate salt.
What are the side effects of piperazine?
Side Effects
- Blurring of vision.
- clumsiness.
- crawling or tingling feeling of the skin.
- irregular, twisting movement, especially of the face, arms, and legs.
- joint pain.
- skin rash or itching.
Is piperazine the same as pyrantel?
The bephenium/piperazine regimen was superior to both the 2-day and 3-day courses of pyrantel pamoate against the hookworm with aggregate cure rates of 58-60% for pyrantel pamoate and 68-85% for bephenium/piperazine.
How do I know if I have pinworms?
Symptoms of pinworm infection may include: Itching of the anal or vaginal area. Insomnia, irritability, teeth grinding and restlessness. Occasional stomach pain and nausea.